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Varespladib methyl Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755689

Varespladib methyl is a selective group II secretory phospholipase A2 inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Varespladib methyl, Inhibitor
Full Product Name
Varespladib methyl
Product Synonym Names
A-002; LY333013
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
394.42
Solubility
DMSO: 100mg/mL (253.54mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H22N2O5
SMILES
O=C(OC)COC1=CC=CC2=C1C(C(C(N)=O)=O)=C(CC)N2CC3=CC=CC=C3
CAS Number
172733-08-3
Target & IC50
phospholipase A2 (PLA2)

Structure of Varespladib methyl, inhibitor

Varespladib methyl Inhibitor – Cat# MBS5755689

Product References and Citations for Varespladib methyl, inhibitor

Bradley JD, et al. A randomized, double-blinded, placebo-controlled clinical trial of LY333013, a selective inhibitor of group II secretory phospholipase A2, in the treatment,of rheumatoid arthritis. J Rheumatol. 2005 Mar;32(3):417-23.
Lewin M, et al. Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral treatment, for Envenomation. Toxins (Basel). 2016 Aug 25;8(9). pii: E248.

Other Notes

Small volumes of Varespladib methyl, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Varespladib methyl purchase

MBS5755689 is an inhibitor targeting Varespladib methyl.
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