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VU0467485 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755705

VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6nM and 78.8nM at the rat and human M4 receptors, respectively). VU0467485 displays selectivity… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VU0467485, Inhibitor
Full Product Name
VU0467485
Product Gene Name
VU0467485, inhibitor
Product Synonym Names
AZ13713945
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
360.41
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C17H17FN4O2S
SMILES
O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(OC)C(F)=C3
CAS Number
1451994-10-7
Target & IC50
Others

Structure of VU0467485, inhibitor

VU0467485 Inhibitor – Cat# MBS5755705

Product References and Citations for VU0467485, inhibitor

Wood MR, et al. Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the treatment,of Schizophrenia. ACS Med Chem Lett. 2016 Dec 16;8(2):233-238.

Other Notes

Small volumes of VU0467485, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VU0467485 purchase

MBS5755705 is an inhibitor targeting VU0467485.
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