WAY-204688 Inhibitor

Name: WAY-204688 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755710
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755710

WAY-204688 is a selective and orally active estrogen receptor inhibitor of NF-kappaB transcriptional activity (IC50: 122+/-30nM for NF-kappaB-luciferase in HAECT-1 cells). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WAY-204688, Inhibitor

Full Product Name

WAY-204688

Product Gene Name

WAY-204688, inhibitor

Product Synonym Names

SIM-688

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

556.62

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C34H31F3N2O2

SMILES

COC1=C([C@H](C2=CC=CC3=C2C=CC=C3)[C@@](C)(C#N)C(N4CCC(C5=CC(C(F)(F)F)=CC=C5)CC4)=O)C=CC=C1

CAS Number

796854-35-8

Target & IC50

NF-kappaB-luc: ic50 122nM (in HAECT-1 cell)
NF-kappaB

Product Categories/Family for WAY-204688, inhibitor

NF-kappab; NF-kappaB

Product References and Citations for WAY-204688, inhibitor

1. Caggiano TJ, et al. Estrogen receptor dependent inhibitors of NF-kappaB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives: pathway selective inhibitors of NF-kappaB, a potential treatment, for rheumatoid arthritis. J Med Chem. 2007 Nov 1;50(22):5245-8.

Other Notes

Small volumes of WAY-204688, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WAY-204688 purchase

MBS5755710 is an inhibitor targeting WAY-204688.