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WWL70 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755715

MBS5755715 is an inhibitor targeting WWL70. WWL70 is a selective alpha/beta hydrolase domain 6 inhibitors (IC50: 70nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WWL70, Inhibitor
Full Product Name
WWL70
Product Gene Name
WWL70, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
437.49
Solubility
DMSO: 17.33mg/mL (39.61mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C27H23N3O3
SMILES
CN(Cc1cccc(c1)-c1ccncc1)C(=O)Oc1ccc(cc1)-c1ccc(cc1)C(N)=O
CAS Number
947669-91-2
Target & IC50
ABHD6: ic50 70nM

Product Categories/Family for WWL70, inhibitor

Cytoskeletal Signaling; Stem Cells

Structure of WWL70, inhibitor

WWL70 Inhibitor – Cat# MBS5755715

Product References and Citations for WWL70, inhibitor

Tanaka M, et al. WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism. J Neuroinflammation. 2017 Jan 10;14(1):7.
Tchantchou F, et al. Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury. J Neurotrauma. 2013 Apr 1;30(7):565-79.

Other Notes

Small volumes of WWL70, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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