YM022 Inhibitor

Name: YM022 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755724
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755724

YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist. YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo. YM022 shows the Ki values of 68 pM and 63nM for CCK-B and… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

YM022, Inhibitor

Full Product Name

YM022

Product Gene Name

YM022, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

516.59

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C32H28N4O3

SMILES

O=C(NC1=CC=CC(C)=C1)N[C@H]2C(N(CC(C3=CC=CC=C3C)=O)C4=CC=CC=C4C(C5=CC=CC=C5)=N2)=O

CAS Number

145084-28-2

Target & IC50

CCR1: ic50 68pM (ki)
CCR2: ic50 63nM (ki)

Product Categories/Family for YM022, inhibitor

Immunology/Inflammation; CCR; Microbiology&virology

Product References and Citations for YM022, inhibitor

Kitano M, et al. Long-lasting cholecystokinin(2) receptor blockade after a single subcutaneous injection of YF476 or YM022. Br J Pharmacol. 2000 Jun;130(3):699-705.
Beinborn M, et al. Small synthetic ligands of the cholecystokinin-B/gastrin receptor can mimic the function of endogenous peptide hormones.Yale J Biol Med. 1998 May-Aug;71(3-4):337-46.

Other Notes

Small volumes of YM022, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YM022 purchase

MBS5755724 is an inhibitor targeting YM022.