(-)-(S)-B-973B Inhibitor

Name: (-)-(S)-B-973B Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755735
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755735

(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of alpha7 nAChR. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

(-)-(S)-B-973B, Inhibitor

Full Product Name

(-)-(S)-B-973B

Product Gene Name

(-)-(S)-B-973B, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

452.5

Solubility

DMSO: 67.5mg/mL (149.17mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C24H26F2N6O

SMILES

O=C(N[C@H](C1=NC(N2CCN(C3=NC=CC=C3)CC2)=CN=C1)C)CCC4=CC=C(F)C(F)=C4

CAS Number

2244989-34-0

Target & IC50

alpha7 nAChR

Product Categories/Family for (-)-(S)-B-973B, inhibitor

Neuroscience; AChR

Product References and Citations for (-)-(S)-B-973B, inhibitor

Garai S, et al. B-973, a Novel alpha7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.

Other Notes

Small volumes of (-)-(S)-B-973B, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (-)-(S)-B-973B purchase

MBS5755735 is an inhibitor targeting (-)-(S)-B-973B.