(+)-JQ1PA Inhibitor – (+)-JQ1 Pa

Name: (+)-JQ1PA Inhibitor; (+)-JQ1 Pa; MyBioSource
Brand: MyBioSource
SKU: MBS5755743
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755743

(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

(+)-JQ1 PA ((+)-JQ1PA), Inhibitor

Full Product Name

(+)-JQ1 PA

Product Gene Name

(+)-JQ1PA, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

437.95

Solubility

Ethanol: 50mg/mL (114.17mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C22H20ClN5OS

SMILES

CC1=C(C)C2=C(S1)N1C(C)=NN=C1[C@H](CC(=O)NCC#C)N=C2C1=CC=C(Cl)C=C1

CAS Number

2115701-93-2

Target & IC50

BET: ic50 10.4nM

In Vitro

The IC50 of (+)-JQ1 PA for BET is 10.4nM, and the IC50 of JQ1 is 14.3nM in MV4;11 cells[1].

Product Categories/Family for (+)-JQ1PA, inhibitor

Chromatin/Epigenetic; Epigenetic Reader Domain

Product References and Citations for (+)-JQ1PA, inhibitor

Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401.

Other Notes

Small volumes of (+)-JQ1PA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (+)-JQ1PA purchase

MBS5755743 is an inhibitor targeting (+)-JQ1PA. Also known as (+)-JQ1 PA.