5-Ethynyl-2'-deoxyuridine Inhibitor

Name: 5-Ethynyl-2'-deoxyuridine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755747
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755747

5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.It is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

5-Ethynyl-2'-deoxyuridine, Inhibitor

Full Product Name

5-Ethynyl-2'-deoxyuridine

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

252.22

Solubility

H2O: 25mg/mL (95.15mM) Need ultrasonic
DMSO: 120mg/mL (475.77mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C11H12N2O5

SMILES

OC[C@H]1O[C@H](C[C@@H]1O)n1cc(C#C)c(=O)[nH]c1=O

CAS Number

61135-33-9

Target & IC50

Alkyl-Chain

Product Categories/Family for 5-Ethynyl-2'-deoxyuridine, inhibitor

PROTAC

Product References and Citations for 5-Ethynyl-2'-deoxyuridine, inhibitor

An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Cavanagh B L, Walker T, Norazit A, et al. Thymidine Analogues for Tracking DNA Synthesis[J]. Molecules, 2011, 16(9):7980-7993.
Zeng C, Pan F, Jones L A, et al. Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system.[J]. Brain Research, 2010, 1319(none):21-32.

Other Notes

Small volumes of 5-Ethynyl-2'-deoxyuridine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 5-Ethynyl-2'-deoxyuridine purchase

MBS5755747 is an inhibitor targeting 5-Ethynyl-2'-deoxyuridine.