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BOC-VAL-CIT-PAB-PNP Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755749

Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Boc-Val-Cit-PAB-PNP, Inhibitor
Full Product Name
Boc-Val-Cit-PAB-PNP
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
644.67
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Boiling Point
8 degree C (lit.)
Formula
C30H40N6O10
SMILES
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1
CAS Number
870487-10-8
Target & IC50
Cleavable
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Product Categories/Family for Boc-Val-Cit-PAB-PNP, inhibitor

Product References and Citations for Boc-Val-Cit-PAB-PNP, inhibitor

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Other Notes

Small volumes of Boc-Val-Cit-PAB-PNP, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5755749 is an inhibitor targeting Boc-Val-Cit-PAB-PNP.
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