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JAK2JH2 Inhibitor – JAK2 JH2 Tracer

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755856

MBS5755856 is an inhibitor targeting JAK2JH2. Also known as JAK2 JH2 Tracer. JAK2 JH2 Tracer is a fluorescent probe for the JAK2 JH2 domain (Kd: 0.2uM). More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JAK2 JH2 Tracer (JAK2JH2), Inhibitor
Full Product Name
JAK2 JH2 Tracer
Product Gene Name
JAK2JH2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
747.73
Solubility
DMSO: 83.3mg/mL (111.40mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C38H27F2N7O6S
SMILES
S=C(NC1=CC2=C(C3(C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)OC2=O)C=C1)N(CC6=CC=C(NC7=NN(C(C8=C(F)C=CC=C8F)=O)C(N)=N7)C=C6)C
CAS Number
2101955-00-2
Target & IC50
Others

Structure of JAK2JH2, inhibitor

JAK2JH2 Inhibitor – Cat# MBS5755856

Product References and Citations for JAK2JH2, inhibitor

Newton AS, et al. JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. ACS Med Chem Lett. 2017 May 17;8(6):614-617.

Other Notes

Small volumes of JAK2JH2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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