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Docosahexaenoic Acid methyl ester Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755995

Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Docosahexaenoic Acid methyl ester, Inhibitor
Full Product Name
Docosahexaenoic Acid methyl ester
Product Synonym Names
Methyl docosahexaenoate; all cis-DHA methyl ester
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
342.51
Solubility
DMSO: 25mg/mL (72.99mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C23H34O2
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OC)=O
CAS Number
2566-90-7
Target & IC50
Others
In Vitro
After the application of methyl docosahexaenoate (DHA-Me), the incidence of sharp waves (SPW) relative to baseline appeared to decrease. In the absence of methyl docosahexaenoate (DHA), when bovine serum albumin (BSA) is exposed to a mixed functional oxidation system of Fe2+ and ascorbic acid (AsA), no new protein bands are produced. However, when BSA was incubated with DHA for only 24 hours, high molecular weight protein bands were observed. The incubation of BSA with 1.0mM DHA resulted in a substantial increase in protein carbonyl content, while the addition of oxygen free radical scavenger resulted in a significant decrease in protein carbonyl content.

Product References and Citations for Docosahexaenoic Acid methyl ester, inhibitor

Taha AY, et al. Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo. Brain Res. 2013 Nov 6;1537:9-17.
Taha AY, et al. Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo. Brain Res. 2013 Nov 6;1537:9-17.
Liu W, et al. Formation of high-molecular-weight protein adducts by methyl docosahexaenoate peroxidation products. Biochim Biophys Acta. 2007 Feb;1774(2):258-66.
Liu W, et al. Formation of high-molecular-weight protein adducts by methyl docosahexaenoate peroxidation products. Biochim Biophys Acta. 2007 Feb;1774(2):258-66.

Other Notes

Small volumes of Docosahexaenoic Acid methyl ester, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Docosahexaenoic Acid methyl ester purchase

MBS5755995 is an inhibitor targeting Docosahexaenoic Acid methyl ester.
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