Rabeprazole Inhibitor

MBS5756232 is an inhibitor targeting Rabeprazole. Rabeprazole is an inhibitor of H(+)-K(+)-exchanging atpase.

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Toda R, Shiramoto M, Komai E, Yoshii K, Hirayama M, Kawabata Y. Pharmacokinetics and Pharmacodynamics of Azeloprazole Sodium, a Novel Proton Pump Inhibitor, in Healthy Japanese Volunteers. J Clin Pharmacol. 2017 Nov 28. doi: 10.1002/jcph.1038. [Epub ahead of print] PubMed PMID: 29193126.
Kinoshita Y, Kato M, Fujishiro M, Masuyama H, Nakata R, Abe H, Kumagai S, Fukushima Y, Okubo Y, Hojo S, Kusano M. Efficacy and safety of twice-daily rabeprazole maintenance therapy for patients with reflux esophagitis refractory to standard once-daily proton pump inhibitor: the Japan-based EXTEND study. J Gastroenterol. 2017 Nov 29. doi: 10.1007/s00535-017-1417-z. [Epub ahead of print] PubMed PMID: 29188387.

Small volumes of Rabeprazole, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.