(+)-Pinanediol Inhibitor

(+)-Pinanediol is an effective inducer of melanogenesis. In S91 cells, it acts by inducing higher levels of pigmentation and synthesis of nitric oxide (NO).

Duporte G, Flaud PM, Geneste E, Augagneur S, Pangui E, Lamkaddam H, Gratien A, Doussin JF, Budzinski H, Villenave E, Perraudin E. Experimental Study of the Formation of Organosulfates from alpha-Pinene Oxidation. Part I: Product Identification, Formation Mechanisms and Effect of Relative Humidity. J Phys Chem A. 2016 Oct 13;120(40):7909-7923. Epub 2016 Sep 29. PubMed PMID: 27611844.
Bellincontro A, Matarese F, D'Onofrio C, Accordini D, Tosi E, Mencarelli F. Management of postharvest grape withering to optimise the aroma of the final wine: A case study on Amarone. Food Chem. 2016 Dec 15;213:378-387. doi: 10.1016/j.foodchem.2016.06.098. Epub 2016 Jun 29. PubMed PMID: 27451194.
Festa RA, Helsel ME, Franz KJ, Thiele DJ. Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection. Chem Biol. 2014 Aug 14;21(8):977-87. doi: 10.1016/j.chembiol.2014.06.009. Epub 2014 Jul 31. PubMed PMID: 25088681; PubMed Central PMCID: PMC4170187.
Frasinyuk MS, Kwiatkowski S, Wagner JM, Evans TJ, Reed RW, Korotkov KV, Watt DS. Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3546-8. doi: 10.1016/j. Bmcl.2014.05.056. Epub 2014 May 27. PubMed PMID: 24915878; PubMed Central PMCID: PMC4120117.

Small volumes of (+)-Pinanediol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756268 is an inhibitor targeting (+)-Pinanediol.