SBA Inhibitor

SBA crosslinker is a sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms. SBA Crosslinker is useful for making antibody-drug conjugates.

Zhao HM, Ma L, Lin D, Han KK, Chun Y, Xu QH. Preparation of cross-linked bimodal mesoporous SBA-15 with numerous pore openings. J Nanosci Nanotechnol. 2012 Dec;12(12):8955-62. PubMed PMID: 23447944.
Bhange P, Sridevi N, Bhange DS, Prabhune A, Ramaswamy V. Immobilization of bile salt hydrolase enzyme on mesoporous SBA-15 for co-precipitation of cholesterol. Int J Biol Macromol. 2014 Feb;63:218-24. doi: 10.1016/j.ijbiomac.2013.11.008. Epub 2013 Nov 25. PubMed PMID: 24286937.
Vinoba M, Bhagiyalakshmi M, Jeong SK, Yoon YI, Nam SC. Immobilization of carbonic anhydrase on spherical SBA-15 for hydration and sequestration of CO2. Colloids Surf B Biointerfaces. 2012 Feb 1;90:91-6. doi: 10.1016/j.colsurfb.2011.10.001. Epub 2011 Oct 6. PubMed PMID: 22024402.
Endo M, Tipper JL, Barton DC, Stone MH, Ingham E, Fisher J. Comparison of wear, wear debris and functional biological activity of moderately crosslinked and non-crosslinked polyethylenes in hip prostheses. Proc Inst Mech Eng H. 2002;216(2):111-22. PubMed PMID: 12022418.

Small volumes of SBA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756277 is an inhibitor targeting SBA. Also known as SBA Crosslinker.