Adamantanine Inhibitor

MBS5756300 is an inhibitor targeting Adamantanine. Adamantanine is an amino acid transport inhibitor.

Thomaston JL, DeGrado WF. Crystal structure of the drug-resistant S31N influenza M2 proton channel. Protein Sci. 2016 Aug;25(8):1551-4. doi: 10.1002/pro.2937. Epub 2016 May 17. PubMed PMID: 27082171; PubMed Central PMCID: PMC4972211.
SzczeA›niak P, Pieczykolan M, Stecko S. The Synthesis of alpha,alpha-Disubstituted alpha-Amino Acids via Ichikawa Rearrangement. J Org Chem. 2016 Feb 5;81(3):1057-74. doi: 10.1021/acs.joc.5b02628. Epub 2016 Jan 12. PubMed PMID: 26726732.
Cai J, Wang X, Zhao B, Yao W, Wang X, Zhu Q, Zeng M. Prevalence, genetic drift of haemagglutinin, and antiviral resistance of influenza A/H3N2 viruses circulating in Shanghai in children during 2009-2012. J Med Virol. 2014 Jun;86(6):1026-33. doi: 10.1002/jmv.23854. Epub 2014 Feb 13. PubMed PMID: 24523140.
Wang L, Lei J, Ma R, Ju H. Host-guest interaction of adamantine with a beta-cyclodextrin-functionalized AuPd bimetallic nanoprobe for ultrasensitive electrochemical immunoassay of small molecules. Anal Chem. 2013 Jul 2;85(13):6505-10. doi: 10.1021/ac401105p. Epub 2013 Jun 14. PubMed PMID: 23725199.

Small volumes of Adamantanine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.