Ertapenem Inhibitor

Ertapenem is a parenteral carbapenem. It has a broad spectrum of antimicrobial activity. It is highly resistant to inactivation by a wide variety of beta-lactamases.

Saunte DML, Jemec GBE. Hidradenitis Suppurativa: Advances in Diagnosis and treatment, JAMA. 2017 Nov 28;318(20):2019-2032. doi: 10.1001/jama.2017.16691. Review. PubMed PMID: 29183082.
Lother SA, Press N. Once-Daily treatment, for Methicillin-Susceptible Staphylococcus aureus Bacteremia: Are They Good Enough. Curr Infect Dis Rep. 2017 Sep 23;19(11):43. doi: 10.1007/s11908-017-0599-0. Review. PubMed PMID: 28942574.
Deshayes S, Coquerel A, Verdon R. Neurological Adverse Effects Attributable to beta-Lactam Antibiotics: A Literature Review. Drug Saf. 2017 Dec;40(12):1171-1198. doi: 10.1007/s40264-017-0578-2. Review. PubMed PMID: 28755095.
Bos JC, van Hest RM, Prins JM. Pharmacokinetics of Antibiotics in Sub-Saharan African Patient Populations: A Systematic Review. Ther Drug Monit. 2017 Aug;39(4):387-398. doi: 10.1097/FTD.0000000000000418. Review. PubMed PMID: 28703719.

Small volumes of Ertapenem, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756334 is an inhibitor targeting Ertapenem.