Tetragastrin Inhibitor

Tetragastrin is the C-terminal tetrapeptide of gastrin. It has the same physiological and pharmacological activity as gastrin.

Tenma T, Yodoya E, Tashima S, Fujita T, Murakami M, Yamamoto A, Muranishi S. Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. Pharm Res. 1993 Oct;10(10):1488-92. PubMed PMID: 8272412.
Komuro Y, Ishihara K, Ohara S, Saigenji K, Hotta K. Effects of tetragastrin on mucus glycoprotein in rat gastric mucosal protection. Gastroenterol Jpn. 1992 Oct;27(5):597-603. PubMed PMID: 1385248.
Tatsuta M, Iishi H, Yamamura H, Taniguchi H. Inhibition by tetragastrin of experimental carcinogenesis in rat colon: effect of wheat bran consumption. Int J Cancer. 1988 Feb 15;41(2):239-42. PubMed PMID: 2828245.
Tatsuta M, Iishi H, Baba M, Taniguchi H. Effect of 6-hydroxydopamine on gastric carcinogenesis and tetragastrin inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1989 Aug 1;49(15):4199-203. PubMed PMID: 2501024.

Small volumes of Tetragastrin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756442 is an inhibitor targeting Tetragastrin.