Tulobuterol Inhibitor

Tulobuterol is mainly used for the prevention and treatment,of bronchial asthma, asthmatic bronchitis and chronic bronchitis. Research shows that it could inhibit rhinovirus infection in primary cultures of human tracheal epithelial cells.

Lin Q, Liu QH, Bao YX. [Efficacy and safety of tulobuterol patch versus oral salbutamol sulfate in children with mild or moderate acute attack of bronchial asthma: a comparative study]. Zhongguo Dang Dai Er Ke Za Zhi. 2013 Jun;15(6):462-5. Chinese. PubMed PMID: 23791063.
Yamaya M, Nishimura H, Nadine L, Kubo H, Ryoichi N. Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells. Physiol Rep. 2013 Aug;1(3):e00041. doi: 10.1002/phy2.41. Epub 2013 Aug 22. PubMed PMID: 24303127; PubMed Central PMCID: PMC3834998.
Ichikawa M, Kodama Y, Yoshimi K, Shiota S, Kotajima M, Nakajyo M, Seyama K, Fukuchi Y, Takahashi K. Effects of transdermal tulobuterol on dyspnea and respiratory function during exercise in patients with chronic obstructive pulmonary disease. J Thorac Dis. 2015 Apr;7(4):687-96. doi: 10.3978/j.issn.2072-1439.2015.04.22. PubMed PMID: 25973235; PubMed Central PMCID: PMC4419310.
Han X, Liu R, Ji L, Hui M, Li Q, Fang L, Bi K. Determination of tulobuterol in rat plasma using a liquid chromatography-tandem mass spectrometry method and its application to a pharmacokinetic study of tulobuterol patch. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jan 1;1008:108-114. doi: 10.1016/j.jchromb.2015.11.017. Epub 2015 Nov 28. PubMed PMID: 26638035.

Small volumes of Tulobuterol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756500 is an inhibitor targeting Tulobuterol.