Cryptating agent 222 Inhibitor

Cryptating agent 222, also named NSC 264495, forms ligands with metal cations. It is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion.

Baumann M, Schaffer E, Greim H. Short-term studies with the cryptating agent hexaoxa-diaza-bicyclo-hexacosane in rats. Arch Toxicol Suppl. 1984;7:427-9. PubMed PMID: 6596011.
Yu Q, Li X, Liu D, Li J. Structural study of a manganese(II) 'picket-fence' porphyrin complex. Acta Crystallogr C Struct Chem. 2015 Jul;71(Pt 7):545-8. doi: 10.1107/S2053229615009304. Epub 2015 Jun 13. PubMed PMID: 26146391.
Prest JE, Fielden PR, Qi Y. Separation of alkali metals using isotachophoresis with cryptand 222 as a leading electrolyte additive. J Chromatogr A. 2012 Oct 19;1260:239-43. doi: 10.1016/j.chroma.2012.08.092. Epub 2012 Sep 2. PubMed PMID: 22989487.
Castaing M, Morel F, Lehn JM. Transport of alkali cations through thin lipid membranes by (222)C10-cryptand, an ionizable mobile carrier. J Membr Biol. 1986;89(3):251-67. PubMed PMID: 3701842.

Small volumes of Cryptating agent 222, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756527 is an inhibitor targeting Cryptating agent 222.