Flusilazole Inhibitor

Flusilazole, an organosilicon fungicide, is used to control fungal infections on a variety of vegetable and fruit crops. It is moderately toxic to animals and has been shown to produce embryotoxicity and birth defects at high doses.

Wang C, Qiu L, Zhao H, Wang K, Zhang H. Dissipation dynamic and residue distribution of flusilazole in mandarin. Environ Monit Assess. 2013 Nov;185(11):9169-76. doi: 10.1007/s10661-013-3244-x. Epub 2013 May 9. PubMed PMID: 23657738.
Ozakca DU, Silah H. Genotoxicity effects of Flusilazole on the somatic cells of Allium cepa. Pestic Biochem Physiol. 2013 Sep;107(1):38-43. doi: 10.1016/j.pestbp.2013.05.001. Epub 2013 May 10. PubMed PMID: 25149233.
Dimopoulou M, Verhoef A, van Ravenzwaay B, Rietjens IM, Piersma AH. Flusilazole induces spatio-temporal expression patterns of retinoic acid-, differentiation- and sterol biosynthesis-related genes in the rat Whole Embryo Culture. Reprod Toxicol. 2016 Sep;64:77-85. doi: 10.1016/j.reprotox.2016.04.003. Epub 2016 Apr 14. PubMed PMID: 27094377.
Yu S, Qin D, Wu Q, Guo X, Han L, Jiang S. Residue and dissipation dynamics of flusilazole in apple and soil. Bull Environ Contam Toxicol. 2011 Mar;86(3):319-22. doi: 10.1007/s00128-011-0203-5. Epub 2011 Feb 3. PubMed PMID: 21290102.

Small volumes of Flusilazole, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756564 is an inhibitor targeting Flusilazole.