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m-PEG11-TOS Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5756582

M-PEG11-Tos is a PEG derivative containing a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. For nucleophilic substitution reactions, the tosyl group is a good leaving group. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
m-PEG11-Tos, Inhibitor
Full Product Name
m-PEG11-Tos
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
626.76
Solubility
DMSO: Soluble
(<1mg/ refers to the product slightly soluble or insoluble)
Formula
C28H50O13S
SMILES
CC1=CC=C(S(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)(=O)=O)C=C1
CAS Number
58320-73-3

Product References and Citations for m-PEG11-Tos, inhibitor

Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750. PubMed PMID: 27572704; PubMed Central PMCID: PMC5004151.
Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. PubMed PMID: 24200843.
Garay RP, El-Gewely R, Armstrong JK, Garratty G, Richette P. Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents. Expert Opin Drug Deliv. 2012 Nov;9(11):1319-23. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30. PubMed PMID: 22931049.

Other Notes

Small volumes of m-PEG11-Tos, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for m-PEG11-Tos purchase

MBS5756582 is an inhibitor targeting m-PEG11-Tos.
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