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Memantine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5756607

Memantine, an amantadine derivative with some dopaminergic effects, has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blockingnMDA receptors. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Memantine, Inhibitor
Full Product Name
Memantine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
179.31
Solubility
DMSO: Soluble
(<1mg/ refers to the product slightly soluble or insoluble)
Formula
C12H21N
SMILES
C1[C@@]2(CC3(CC(C2)C[C@@]1(C3)C)N)C
CAS Number
19982-08-2

Product References and Citations for Memantine, inhibitor

Chen R, Chan PT, Chu H, Lin YC, Chang PC, Chen CY, Chou KR. treatment,effects between monotherapy of donepezil versus combination with memantine for Alzheimer disease: A meta-analysis. PLoS One. 2017 Aug 21;12(8):e0183586. doi: 10.1371/journal.pone.0183586. eCollection 2017. PubMed PMID: 28827830; PubMed Central PMCID: PMC5565113.
Deardorff WJ, Grossberg GT. A fixed-dose combination of memantine extended-release and donepezil in the treatment,of moderate-to-severe Alzheimer's disease. Drug Des Devel Ther. 2016 Oct 3;10:3267-3279. eCollection 2016. Review. PubMed PMID: 27757016; PubMed Central PMCID: PMC5055113.
Greig SL. Memantine ER/Donepezil: A Review in Alzheimer's Disease. CNS Drugs. 2015 Nov;29(11):963-70. doi: 10.1007/s40263-015-0287-2. Review. PubMed PMID: 26519339.
Matsunaga S, Kishi T, Iwata N. Memantine monotherapy for Alzheimer's disease: a systematic review and meta-analysis. PLoS One. 2015 Apr 10;10(4):e0123289. doi: 10.1371/journal.pone.0123289. eCollection 2015. Review. PubMed PMID: 25860130; PubMed Central PMCID: PMC4393306.

Other Notes

Small volumes of Memantine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Memantine purchase

MBS5756607 is an inhibitor targeting Memantine.
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