Dextrothyroxine Inhibitor

Dextrothyroxine could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.

Schwartz ID, Bercu BB. Dextrothyroxine in the treatment,of generalized thyroid hormone resistance in a boy homozygous for a defect in the T3 receptor. Thyroid. 1992 Spring;2(1):15-9. PubMed PMID: 1525565.
Krawczynska H, Wojcik-Musialek K, Illig R. 10 years of successful treatment,with dextrothyroxine in a girl with TSH-induced hyperthyroidism. Horm Res. 1991;35(5):213-6. PubMed PMID: 1802825.
Hazenberg HJ, Muller CJ, Kerckhoffs HP, Erkelens DW. Dextrothyroxine induced hyperthyroidism in a patient with heterozygous familial hypercholesterolaemia. Neth J Med. 1987 Oct;31(3-4):117-21. PubMed PMID: 3683682.
Hankins JH, Heise CM, Cowan RJ. Iatrogenic hyperthyroidism secondary to dextrothyroxine administration. Clin Nucl Med. 1984 Jan;9(1):17-9. PubMed PMID: 6697613.

Small volumes of Dextrothyroxine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5756724 is an inhibitor targeting Dextrothyroxine.