Azatadine Inhibitor

Azatadine is histamine and cholinergic inhibitor (IC50: 6.5nM and 10nM, respectively).

Jacobson K A, Ivanov A A, de Castro S, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal, 2009, 5(1): 75-89.
Jacobson K A, Ivanov A A, de Castro S, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal, 2009, 5(1): 75-89.
Hardwick J C, Ehrlich Y H, Hendley E D. Extracellular ATP stimulates norepinephrine uptake in PC12 cells. Journal of Neurochemistry, 1989, 53(5):1512-1518.
Hardwick J C, Ehrlich Y H, Hendley E D. Extracellular ATP stimulates norepinephrine uptake in PC12 cells. Journal of Neurochemistry, 1989, 53(5):1512-1518.
Liu P, Lalor D, Bowser S S, et al. Regulation of arachidonic acid release and prostaglandin E2 production in thymic epithelial cells by ATPgammaS and transforming growth factor-alpha. Cellular immunology, 1998, 188(2): 81-88.
Liu P, Lalor D, Bowser S S, et al. Regulation of arachidonic acid release and prostaglandin E2 production in thymic epithelial cells by ATPgammaS and transforming growth factor-alpha. Cellular immunology, 1998, 188(2): 81-88.

Small volumes of Azatadine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5757087 is an inhibitor targeting Azatadine.