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GSKJ5 Inhibitor – GSK J5

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5757302

GSK J5 is an inactive isomer of GSK J4 and a cell-permeable ester derivative of inactive control GSK J2. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK J5 (GSKJ5), Inhibitor
Full Product Name
GSK J5
Product Gene Name
GSKJ5, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
417.5
Solubility
DMSO: <41.75mg/ml
Ethanol: <41.75mg/ml
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H27N5O2
SMILES
CCOC(CCNC1=CC(N2CCC3=CC=CC=C3CC2)=NC(C4=CN=CC=C4)=N1)=O
CAS Number
1394854-51-3
In Vitro
It is worth noting that the injection of GSK-J4 attenuated disease progression in a human AML xenograft mouse model. treatment with GSK-J4 mainly resulted in the downregulation of DNA replication and cell cycle-related pathways and prevents the expression of HOX, a key cancer gene. ChIP-qPCR verified the increased H3K27me3 enrichment in the HOX gene transcription initiation site [1].

Other Notes

Small volumes of GSKJ5, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSKJ5 purchase

MBS5757302 is an inhibitor targeting GSKJ5. Also known as GSK J5.
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