• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Vanoxerine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5757956

MBS5757956 is an inhibitor targeting Vanoxerine. Vanoxerine is an antagonist of dopamine transporter (Ki: 16.9nM). More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Vanoxerine, Inhibitor
Full Product Name
Vanoxerine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
450.56
Solubility
DMSO: Soluble
(<1mg/ refers to the product slightly soluble or insoluble)
Formula
C28H32F2N2O
SMILES
C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
CAS Number
67469-69-6
In Vitro
As an antagonist of DAT, vanoxerine is developed for treatment of Parkinson's disease and depression but has no effect on these diseases. Vanoxerine is also found to have desirable cardiac antiarrhythmic properties. It is a blocker of cardiac hERG (IC50:0.84nM). It also blocks the ICa,L and hNav1.5 channel (IC50: 320nM and 830nM, respectively). Vanoxerine does not significantly prolong Purkinje fiber APD60 and APD90 and has no significant effect on QT or TDR.

Product Categories/Family for Vanoxerine, inhibitor

GPCR/G Protein; Neuroscience

Other Notes

Small volumes of Vanoxerine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000