Hederacolchiside A1 Inhibitor

Name: Hederacolchiside A1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758028
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758028

Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacolchiside A1 shows antiproliferation activities in three… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Hederacolchiside A1, Inhibitor

Full Product Name

Hederacolchiside A1

Form/Format

Solid. Powder

Purity/Purification

99.92%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

897.10

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C47H76O16

SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@H](CO[C@H]2O[C@H]3CC[C@]4([C@H](C3(C)C)CC[C@@]5([C@@H]4CC=C6[C@]5(CC[C@@]7([C@H]6CC(CC7)(C)C)C(=O)O)C)C)C)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O)O)O)O

CAS Number

106577-39-3

Target & IC50

MEK
ERK

Product Categories/Family for Hederacolchiside A1, inhibitor

MAPK; MEK; PI3K/Akt/mTOR; MAPK; Anti-infection

Product References and Citations for Hederacolchiside A1, inhibitor

Wang L, Wang Z, Su S, et al. Synthesis and cytotoxicity of oleanolic acid trisaccharide saponins[J]. Carbohydrate Research, 2017, 442:9-16.
Wang L, Wang Z, Su S, et al. Synthesis and cytotoxicity of oleanolic acid trisaccharide saponins[J]. Carbohydrate Research, 2017, 442:9-16.
Barthomeuf C, Boivin D, Richard Beliveau. Inhibition of HUVEC tubulogenesis by hederacolchiside-A1 is associated with plasma membrane cholesterol sequestration and activation of the Ha-Ras/MEK/ERK cascade[J]. Cancer Chemotherapy & Pharmacology, 2004, 54(5):432-440.
Barthomeuf C, Boivin D, Richard Beliveau. Inhibition of HUVEC tubulogenesis by hederacolchiside-A1 is associated with plasma membrane cholesterol sequestration and activation of the Ha-Ras/MEK/ERK cascade[J]. Cancer Chemotherapy & Pharmacology, 2004, 54(5):432-440.
Delmas F, Giorgio C D, Elias R, et al. Antileishmanial activity of three saponins isolated from ivy, alpha-hederin, beta-hederin and hederacolchiside A1, as compared to their action on mammalian cells cultured in vitro.[J]. Planta Medica, 2000, 66(04):343-347.
Delmas F, Giorgio C D, Elias R, et al. Antileishmanial activity of three saponins isolated from ivy, alpha-hederin, beta-hederin and hederacolchiside A1, as compared to their action on mammalian cells cultured in vitro.[J]. Planta Medica, 2000, 66(04):343-347.

Other Notes

Small volumes of Hederacolchiside A1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hederacolchiside A1 purchase

MBS5758028 is an inhibitor targeting Hederacolchiside A1.