Tocofersolan Inhibitor

Tocofersolan is a polyethylene glycol derivative of alpha-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment,of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.

Thebaut, A, Nemeth A, Le Mouhar, J, et al. Oral Tocofersolan Corrects or Prevents Vitamin E Deficiency in Children With Chronic Cholestasis[J]. Journal of Pediatric Gastroenterology & Nutrition, 2016, 63(6):1.
Roongpraiwan R, Suthutvoravut U, Feungpean B, et al. Effect of oral vitamin E supplementation in children with cholestasis.[J]. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, 85 Suppl 4:S1199.
Rehim WM, et al. Antioxidant capacity in Fasciola hepatica patients before and after treatment,with triclabendazole alone or in combination with ascorbic acid (vitamin C) and tocofersolan (vitamin E). Arzneimittelforschung. 2003;53(3):214-20.

Small volumes of Tocofersolan, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758168 is an inhibitor targeting Tocofersolan.