Elagolix sodium Inhibitor

Name: Elagolix sodium Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758197
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758197

Elagolix sodium is a GnRH receptor (GnRHR) antagonist (IC50 and Ki of 0.25 and 3.7nM, respectively). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Elagolix sodium, Inhibitor

Full Product Name

Elagolix sodium

Product Synonym Names

NBI-56418 sodium

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

653.57

Solubility

DMSO: 50mg/mL (76.50mM)
H2O: 50mg/mL (76.50mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C32H29F5N3NaO5

SMILES

COc1cccc(-c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(CC(NCCCC(=O)[O-])c3ccccc3)c2=O)c1F.[Na+]

CAS Number

832720-36-2

Target & IC50

GnRHR: ic50 3.7nM

In Vitro

Elagolix sodium for the treatment of women with moderate to severe endometriosis-associated pain[1]

Product Categories/Family for Elagolix sodium, inhibitor

GPCR/G Protein; GNRH Receptor

Product References and Citations for Elagolix sodium, inhibitor

Barra F, Scala C, Ferrero S2.Elagolix sodium for the treatment,of women with moderate to severe endometriosis-associated pain.Drugs Today (Barc). 2019 Apr;55(4):237-246.
Barra F, Scala C, Ferrero S2.Elagolix sodium for the treatment,of women with moderate to severe endometriosis-associated pain.Drugs Today (Barc). 2019 Apr;55(4):237-246.
Elagolix (Orilissa)--an oral GnRH antagonist for endometriosis pain.[J]. The Medical letter on drugs and therapeutics, 2018.
Elagolix (Orilissa)--an oral GnRH antagonist for endometriosis pain.[J]. The Medical letter on drugs and therapeutics, 2018.
Kim SM, et al. Discovery of an Orally Bioavailable Gonadotropin-Releasing Hormone Receptor Antagonist. J Med Chem. 2016 Oct 13;59(19):9150-9172. Epub 2016 Sep 27.

Other Notes

Small volumes of Elagolix sodium, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Elagolix sodium purchase

MBS5758197 is an inhibitor targeting Elagolix sodium.