Rotundine Inhibitor

Name: Rotundine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758266
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758266

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rotundine, Inhibitor

Full Product Name

Rotundine

Product Synonym Names

L-Tetrahydropalmatine; (-)-Tetrahydropalmatine; Caseanine; Gindarine

Form/Format

Solid. Powder

Purity/Purification

99.80%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

355.43

Solubility

DMSO: 8mg/mL (22.5mM)
Ethanol: <1mg/mL
Water: <1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C21H25NO4

SMILES

[H][C@@]12CC3=CC=C(OC)C(OC)=C3CN1CCC1=C2C=C(OC)C(OC)=C1

CAS Number

483-14-7

Target & IC50

D1 receptor: ic50
5-HT1A
D2 receptor
D3 receptor

Product Categories/Family for Rotundine, inhibitor

Neuroscience; GPCR/G Protein

Product References and Citations for Rotundine, inhibitor

Wang JB, et al. Future Med Chem, 2012, 4(2), 177-186.
Wang JB, et al. Future Med Chem, 2012, 4(2), 177-186.
Liu YL, et al. Acta Pharmacol Sin, 2005, 26(5), 533-538.
Liu YL, et al. Acta Pharmacol Sin, 2005, 26(5), 533-538.

Other Notes

Small volumes of Rotundine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rotundine purchase

MBS5758266 is an inhibitor targeting Rotundine.