Pachymic acid Inhibitor

Name: Pachymic acid Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758269
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758269

Pachymic acid is a natural product, and inhibits Akt and ERK signaling pathways. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pachymic acid, Inhibitor

Full Product Name

Pachymic acid

Product Synonym Names

3-O-Acetyltumulosic acid

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

528.77

Solubility

DMSO: 7mg/mL (13.24mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C33H52O5

SMILES

[H][C@]1([C@@H](CCC(=C)C(C)C)C(O)=O)[C@H](O)C[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](OC(C)=O)C(C)(C)[C@]1([H])CC3

CAS Number

29070-92-6

Target & IC50

Akt
ERK

Cell Research

The anti-proliferative ability of PA on lung cancer cells was assessed by MTT, colony formation and EdU proliferation assays. Flow cytometric analysis was used to detect cell cycle changes. Apoptosis was determined by annexin V/PI double-staining and the DNA ladder formation assays. The expressions of the apoptosis-related proteins were analysed by western blot[1].

Product Categories/Family for Pachymic acid, inhibitor

Cytoskeletal Signaling; Akt; PI3K/Akt/mTOR signaling; MAPK

Product References and Citations for Pachymic acid, inhibitor

Ma J, et al. Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer
Ma J, et al. Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer
Chen Y, et al. Pachymic acid inhibits tumorigenesis in gallbladder carcinoma cells. Int J Clin Exp Med. 2015 Oct
Chen Y, et al. Pachymic acid inhibits tumorigenesis in gallbladder carcinoma cells. Int J Clin Exp Med. 2015 Oct

Other Notes

Small volumes of Pachymic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pachymic acid purchase

MBS5758269 is an inhibitor targeting Pachymic acid.