• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Verucerfont Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758298

Verucerfont is an antagonist of corticotropin-releasing factor receptor 1 (CRF1). More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Verucerfont, Inhibitor
Full Product Name
Verucerfont
Product Synonym Names
GSK561679; NBI77860
Form/Format
Solid. Powder
Purity/Purification
99.95%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
406.48
Solubility
DMSO: 86.7mg/mL (213.29mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H26N6O2
SMILES
CCC(Nc1cc(C)nc2c(-c3ccc(OC)cc3C)c(C)nn12)c1nc(C)no1
CAS Number
885220-61-1
Target & IC50
CRLR/RAMP1 cell assay: ic50 1nM
CRLR/RAMP2 cell assay: ic50 300nM

Product Categories/Family for Verucerfont, inhibitor

Product References and Citations for Verucerfont, inhibitor

Schwandt M L, Cortes C R, Kwako L E, et al. The CRF1 Antagonist Verucerfont in Anxious Alcohol Dependent Women: Translation of Neuroendocrine, but not of Anti-Craving Effects[J]. Neuropsychopharmacology, 2016.
Schwandt M L, Cortes C R, Kwako L E, et al. The CRF1 Antagonist Verucerfont in Anxious Alcohol Dependent Women: Translation of Neuroendocrine, but not of Anti-Craving Effects[J]. Neuropsychopharmacology, 2016.
Zorrilla E P, Heilig M, De Wit H, et al. Behavioral, biological, and chemical perspectives on targeting CRF1 receptor antagonists to treat alcoholism[J]. Drug and Alcohol Dependence, 2013, 128(3):175-186.
Zorrilla E P, Heilig M, De Wit H, et al. Behavioral, biological, and chemical perspectives on targeting CRF1 receptor antagonists to treat alcoholism[J]. Drug and Alcohol Dependence, 2013, 128(3):175-186.

Other Notes

Small volumes of Verucerfont, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Verucerfont purchase

MBS5758298 is an inhibitor targeting Verucerfont.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000