Inarigivir Inhibitor

Name: Inarigivir Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758299
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758299

Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Inarigivir, Inhibitor

Full Product Name

Inarigivir

Product Synonym Names

ORI-9020

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

587.5

Solubility

DMSO: Soluble
(<1mg/ refers to the product slightly soluble or insoluble)

Formula

C20H23N7O10PS

SMILES

NC1=C(N=CN2[C@@H]3O[C@](COP(O[C@]4[C@@H](OC)[C@](N5C=CC(NC5=O)=O)O[C@@H]4CO)(S)=O)[C@@H](O)C3)C2=NC=N1

CAS Number

475650-36-3

In Vitro

Inarigivir (100mg/kg/day, I.p.) significantly reduces viral DNA in the liver and shows anti-HBV activity similar to ADV positive control. Inarigivir does not affect levels of HBV RNA in the liver, levels of HBeAg in serum, or mean titers of HBsAg. The minimal effective dose is identified to be between 1.6 and 0.5mg/kg/day using liver HBV DNA values.

Product Categories/Family for Inarigivir, inhibitor

Microbiology/Virology; HBV

Product References and Citations for Inarigivir, inhibitor

Iyer RP, et al. Anti-hepatitis B virus activity of ORI-9020, a novel phosphorothioate dinucleotide, in a transgenic mouse model. Antimicrob Agents Chemother. 2004 Jun;48(6):2318-20.

Other Notes

Small volumes of Inarigivir, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Inarigivir purchase

MBS5758299 is an inhibitor targeting Inarigivir.