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CDN1163 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758300

CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDN1163, Inhibitor
Full Product Name
CDN1163
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
320.39
Solubility
DMSO: 50mg/mL (156.06mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C20H20N2O2
SMILES
Cc1ccc2cccc(NC(=O)c3ccc(OC(C)C)cc3)c2n1
CAS Number
892711-75-0
Target & IC50
Calcium Channel

Structure of CDN1163, inhibitor

CDN1163 Inhibitor – Cat# MBS5758300

Product References and Citations for CDN1163, inhibitor

Kang S, Dahl R, Hsieh W, et al. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders[J]. Journal of Biological Chemistry, 2015:jbc.M115.705012.
Kang S, Dahl R, Hsieh W, et al. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders[J]. Journal of Biological Chemistry, 2015:jbc.M115.705012.
Rizwan, Qaisar, Shylesh, et al. Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness.[J]. Redox biology, 2018.
Rizwan, Qaisar, Shylesh, et al. Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness.[J]. Redox biology, 2018.
Kang S, et al. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders. J Biol Chem. 2016 Mar 4;291(10):5185-98.
Singh R, et al. A role for calcium in resistin transcriptional activation in diabetic hearts. Sci Rep. 2018 Oct 23;8(1):15633.

Other Notes

Small volumes of CDN1163, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDN1163 purchase

MBS5758300 is an inhibitor targeting CDN1163.
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