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Ceftaroline fosamil Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758303

Ceftaroline fosamil is a cephalosporin, with activity against Gram-positive pathogens. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ceftaroline fosamil, Inhibitor
Full Product Name
Ceftaroline fosamil
Product Synonym Names
TAK-599; PPI0903
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
744.74
Solubility
DMSO: 14mg/mL (32.22mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H25N8O10PS4
SMILES
CCON=C(C1=NSC(=N1)NP(=O)(O)O)C(=O)NC2C3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)O.CC(=O)[O-]
CAS Number
400827-46-5
Target & IC50
Bacterial
Antibiotic
In Vitro
Ceftaroline fosamil 600 mg given every 12 h was superior to ceftriaxone 2 g given every 24 hours for the treatment of Asian patients with PORT III-IV community-acquired pneumonia. These data suggest that ceftaroline fosamil should be regarded as an alternative to ceftriaxone in empirical treatment,regimens for this patient population.

Product References and Citations for Ceftaroline fosamil, inhibitor

Zhong, Nan Shan, Sun, Tieying, Zhuo, Chao,et,al. Ceftaroline fosamil versus ceftriaxone for the treatment,of Asian patients with community-acquired pneumonia: a randomised, controlled, double-blind, phase 3, non-inferiority with nested superiority trial[J]. Lancet Infectious Diseases, 2015, 15(2):161-171.
Zhong, Nan Shan, Sun, Tieying, Zhuo, Chao,et,al. Ceftaroline fosamil versus ceftriaxone for the treatment,of Asian patients with community-acquired pneumonia: a randomised, controlled, double-blind, phase 3, non-inferiority with nested superiority trial[J]. Lancet Infectious Diseases, 2015, 15(2):161-171.
So W, et al. Comparison of in vivo and in vitro pharmacodynamics of a humanized regimen of 600 milligrams of Ceftaroline Fosamil every 12 hours against Staphylococcus aureus at initial inocula of 106 and 108 CFU per milliliter. Antimicrob Agents Chemother. 2014 Nov;58(11):6931-3.
So W, et al. Comparison of in vivo and in vitro pharmacodynamics of a humanized regimen of 600 milligrams of Ceftaroline Fosamil every 12 hours against Staphylococcus aureus at initial inocula of 106 and 108 CFU per milliliter. Antimicrob Agents Chemother. 2014 Nov;58(11):6931-3.

Other Notes

Small volumes of Ceftaroline fosamil, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ceftaroline fosamil purchase

MBS5758303 is an inhibitor targeting Ceftaroline fosamil.
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