DMAT Inhibitor

MBS5758304 is an inhibitor targeting DMAT. DMAT is a potent and specific inhibitor of CK2(IC50 value of 130nM).

Lawnicka H, Kowalewicz-Kulbat M, Sicinska P, et al. Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro[J]. Cell & Tissue Research, 2010, 340(2):371-379.
Lawnicka H, Kowalewicz-Kulbat M, Sicinska P, et al. Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro[J]. Cell & Tissue Research, 2010, 340(2):371-379.
Sass, Gabriele. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT[J]. International Journal of Oncology, 2011, 39(2).
Sass, Gabriele. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT[J]. International Journal of Oncology, 2011, 39(2).

Small volumes of DMAT, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.