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Avatrombopag Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758315

Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Avatrombopag, Inhibitor
Full Product Name
Avatrombopag
Product Synonym Names
AKR-501; E5501; YM477
Form/Format
Solid. Powder
Purity/Purification
99.01%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
649.65
Solubility
DMSO: 32mg/mL (49.26mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C29H34Cl2N6O3S2
SMILES
O=C(Nc1nc(-c2cc(Cl)cs2)c(N2CCN(C3CCCCC3)CC2)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1
CAS Number
570406-98-3
Target & IC50
TPO
In Vitro
Avatrombopag is treatment of thrombocytopenia in patients with CLD who are scheduled to undergo a procedure[1].

Structure of Avatrombopag, inhibitor

Avatrombopag Inhibitor – Cat# MBS5758315

Product References and Citations for Avatrombopag, inhibitor

Xu H, Cai R. Avatrombopag for the treatment,of thrombocytopenia in patients with chronic liver disease.Expert Rev Clin Pharmacol. 2019 Sep;12(9):859-865
Al-Samkari H. Avatrombopag maleate for the treatment,of periprocedural thrombocytopenia in patients with chronic liver disease.Drugs Today (Barc). 2018 Nov;54(11):647-655.

Other Notes

Small volumes of Avatrombopag, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Avatrombopag purchase

MBS5758315 is an inhibitor targeting Avatrombopag.
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