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Alsterpaullone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758323

Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alsterpaullone, Inhibitor
Full Product Name
Alsterpaullone
Form/Format
Solid. Powder
Purity/Purification
99.39%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
293.28
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C16H11N3O3
SMILES
O=C1Cc2c([nH]c3ccc([N+](=O)[O-])cc23)-c2ccccc2N1
CAS Number
237430-03-4
Target & IC50
Cdk1/cyclin B: ic50 35nM
cdk2/cyclin A: ic50 15nMCD
K2/Cyc E: ic50 200nM
CDK5/p35: ic50 40nM

Product References and Citations for Alsterpaullone, inhibitor

Cui C, Wang Y, Wang Y, et al. Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect[J]. Journal of Analytical Methods in Chemistry, 2013, 2013:1-5.
Cui C, Wang Y, Wang Y, et al. Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect[J]. Journal of Analytical Methods in Chemistry, 2013, 2013:1-5.
Faria C C, Agnihotri S, Mack S C, et al. Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma[J]. Oncotarget, 2015, 6(25):21718-21729.
Faria C C, Agnihotri S, Mack S C, et al. Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma[J]. Oncotarget, 2015, 6(25):21718-21729.

Other Notes

Small volumes of Alsterpaullone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Alsterpaullone purchase

MBS5758323 is an inhibitor targeting Alsterpaullone.
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