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6-(Dimethylamino)purine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758340

MBS5758340 is an inhibitor targeting 6-(Dimethylamino)purine. 6-(Dimethylamino)purine is a serine threonine protein kinase and CDK inhibitor More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
6-(Dimethylamino)purine, Inhibitor
Full Product Name
6-(Dimethylamino)purine
Product Synonym Names
N,N-Dimethyladenine
Form/Format
Solid. Powder
Purity/Purification
99.49%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
163.18
Solubility
DMSO: 32mg/mL (196.1mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Boiling Point
156-157 degree
Formula
C7H9N5
SMILES
CN(C)c1ncnc2[nH]cnc12
CAS Number
938-55-6
Target & IC50
CDK
serine threonine protein kinase
In Vitro
The apoptosis was induced by 6-dimethylaminopurine(6-DMAP) in a dose- and time-dependent manner and treatment, for 16 hours at a concentration of 5mM induced apparent DNA fragmentation, phosphatidylserine externalization and lowering of the mitochondrial membrane potential, which are typical markers of apoptosis[1].

Product Categories/Family for 6-(Dimethylamino)purine, inhibitor

Cell Cycle/Checkpoint; Apoptosis

Structure of 6-(Dimethylamino)purine, inhibitor

6-(Dimethylamino)purine Inhibitor – Cat# MBS5758340

Product References and Citations for 6-(Dimethylamino)purine, inhibitor

Nakashima M, Cui Z G, Tabuchi Y, et al. Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes in gene expression in human lymphoma U937 cells[J]. Anticancer research, 2008, 28(2A):609-620.
Neant I, Guerrier P. 6-Dimethylaminopurine blocks starfish oocyte maturation by inhibiting a relevant protein kinase activity[J]. Experimental Cell Research, 1988, 176(1):0-79.

Other Notes

Small volumes of 6-(Dimethylamino)purine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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