2-methoxycinnamaldehyde Inhibitor

2-Methoxycinnamaldehyde (2-MCA) is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.

Perng D S, Tsai Y H, Cherng J, et al. Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.[J]. Drug Design Development & Therapy, 2016, 10(7):141-153.
Perng D S, Tsai Y H, Cherng J, et al. Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.[J]. Drug Design Development & Therapy, 2016, 10(7):141-153.
Young-Hee J, Soo-A K. 2-Methoxycinnamaldehyde inhibits the TNF-alpha-induced proliferation and migration of human aortic smooth muscle cells[J]. International Journal of Molecular Medicine, 2017, 39(1):191-198.
Young-Hee J, Soo-A K. 2-Methoxycinnamaldehyde inhibits the TNF-alpha-induced proliferation and migration of human aortic smooth muscle cells[J]. International Journal of Molecular Medicine, 2017, 39(1):191-198.
Wong HY, et al. Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo. Phytother Res. 2016 Feb;30(2):331-40.
Liu YH, et al. Cinnamomum verum ingredient 2-methoxycinnamaldehyde: a new antiproliferative drug targeting topoisomerase I and II in human lung squamous cell carcinoma NCI-H520 cells. Eur J Cancer Prev. 2017 Jul;26(4):314-323.

Small volumes of 2-methoxycinnamaldehyde, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758347 is an inhibitor targeting 2-methoxycinnamaldehyde.