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4-Methylbenzylidene camphor Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758358

4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations,specifically UV B radiation, also has estrogenic activities. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
4-Methylbenzylidene camphor, Inhibitor
Full Product Name
4-Methylbenzylidene camphor
Product Synonym Names
4-MBC; Enzacamene
Form/Format
Solid. Powder
Purity/Purification
99.59%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
254.37
Solubility
DMSO: 47mg/mL (184.77mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H22O
SMILES
Cc1ccc(C=C2C(=O)C3(C)CCC2C3(C)C)cc1
CAS Number
36861-47-9
Target & IC50
AChE
In Vitro
4-Methylbenzylidene camphor has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation. In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor[1]

Product References and Citations for 4-Methylbenzylidene camphor, inhibitor

Stefan D, Kirsten M, Margret S, et al. Estrogen Target Gene Regulation and Coactivator Expression in Rat Uterus after Developmental Exposure to the Ultraviolet Filter 4-Methylbenzylidene Camphor[J]. Endocrinology(5):5.
Stefan D, Kirsten M, Margret S, et al. Estrogen Target Gene Regulation and Coactivator Expression in Rat Uterus after Developmental Exposure to the Ultraviolet Filter 4-Methylbenzylidene Camphor[J]. Endocrinology(5):5.
Changwon, Yang, Whasun, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells.[J]. Reproductive toxicology (Elmsford, N.Y.), 2018.
Changwon, Yang, Whasun, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells.[J]. Reproductive toxicology (Elmsford, N.Y.), 2018.

Other Notes

Small volumes of 4-Methylbenzylidene camphor, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 4-Methylbenzylidene camphor purchase

MBS5758358 is an inhibitor targeting 4-Methylbenzylidene camphor.
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