Ademetionine Inhibitor

Ademetionine is an intermediate metabolite of methionine, for treatment,of primary biliary cirrhosis and major depressive disorder.

Ivashkin V T, Maevskaya M V, Kobalava Z D, et al. Open-label study of ademetionine for the treatment,of intrahepatic cholestasis associated with alcoholic liver disease.[J]. Minerva Gastroenterologica E Dietologica, 2018.
Ivashkin V T, Maevskaya M V, Kobalava Z D, et al. Open-label study of ademetionine for the treatment,of intrahepatic cholestasis associated with alcoholic liver disease.[J]. Minerva Gastroenterologica E Dietologica, 2018.
Bressa G M. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies[J]. Acta Neurol Scand Suppl.:7-14.
Bressa G M. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies[J]. Acta Neurol Scand Suppl.:7-14.

Small volumes of Ademetionine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758367 is an inhibitor targeting Ademetionine.