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WKYMVM Inhibitor – 2tfa

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758377

MBS5758377 is an inhibitor targeting WKYMVM. Also known as WKYMVM 2TFA (187986-17-0(free base)). WKYMVM 2TFA is a N-formyl peptide receptor (FPR1) agonist. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WKYMVM 2TFA, Inhibitor
Full Product Name
WKYMVM 2TFA (187986-17-0(free base))
Product Gene Name
WKYMVM, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
856.11
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C41H61N9O7S2
SMILES
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
In Vitro
Neutrophils are activated by WKYMVM through FPRL1 and that FPRL2 is a chemotactic receptor transducing signals in myeloid cells[1].

Product References and Citations for WKYMVM, inhibitor

Christophe T, Karlsson A, Dugave C, et al. The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2[J]. Journal of Biological Chemistry, 2001, 276(24):21585-21593.
Kim H, Noh E K, Lee E J, et al. Enhanced bactericidal function by WKYMVm in patients with acute leukemia[J]. Leukemia Research, 2008, 32(5):717-725.

Other Notes

Small volumes of WKYMVM, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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