Ripasudil Inhibitor

Ripasudil free base is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.

Pantelidis G E, Vasilakakis M, Manganaris G A, et al. Antioxidant capacity, phenol, anthocyanin and ascorbic acid contents in raspberries, blackberries, red currants, gooseberries and Cornelian cherries[J]. Food Chemistry, 2013, 102(3):773-778.
Takatoshi U, Megumi H, Reiko Y, et al. The Anti-Inflammatory Effect of Ripasudil (K-115), a Rho Kinase (ROCK) Inhibitor, on Endotoxin-Induced Uveitis in Rats[J]. Investigative Opthalmology & Visual Science, 2017, 58(12):5584-.
Takatoshi U, Megumi H, Reiko Y, et al. The Anti-Inflammatory Effect of Ripasudil (K-115), a Rho Kinase (ROCK) Inhibitor, on Endotoxin-Induced Uveitis in Rats[J]. Investigative Opthalmology & Visual Science, 2017, 58(12):5584-.
Isobe T, Mizuno K, Kaneko Y, et al. Effects of K-115, a Rho-Kinase Inhibitor, on Aqueous Humor Dynamics in Rabbits[J]. Current Eye Research, 2014, 39(8):813-822.
Isobe T, Mizuno K, Kaneko Y, et al. Effects of K-115, a Rho-Kinase Inhibitor, on Aqueous Humor Dynamics in Rabbits[J]. Current Eye Research, 2014, 39(8):813-822.

Small volumes of Ripasudil, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758386 is an inhibitor targeting Ripasudil. Also known as Ripasudil free base.