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Hexa-D-arginine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758389

Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Hexa-D-arginine, Inhibitor
Full Product Name
Hexa-D-arginine
Form/Format
Solid. Powder
Purity/Purification
100.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
954.14
Solubility
H2O: 50mg/mL (52.40mM) Need ultrasonic
DMSO: 5mg/mL (5.24mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C36H75N25O6
SMILES
C(C[C@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N)N)CN=C(N)N
CAS Number
673202-67-0
Target & IC50
Furin: ic50 106nM (KI)
PACE4: ic50 580nM (KI)
PC1: ic50 13.2mM (ki)

Product References and Citations for Hexa-D-arginine, inhibitor

Sarac M S, Cameron A, Lindberg I. The Furin Inhibitor Hexa-D-Arginine Blocks the Activation of Pseudomonas aeruginosa Exotoxin A In Vivo[J]. Infection and Immunity, 2002, 70(12):7136-7139.
Sarac M S, Cameron A, Lindberg I. The Furin Inhibitor Hexa-D-Arginine Blocks the Activation of Pseudomonas aeruginosa Exotoxin A In Vivo[J]. Infection and Immunity, 2002, 70(12):7136-7139.
Sarac M S, Peinado J R, Leppla S H, et al. Protection against Anthrax Toxemia by Hexa-D-Arginine In Vitro and In Vivo[J]. Infection and Immunity, 2004, 72(1):602-605.
Sarac M S, Peinado J R, Leppla S H, et al. Protection against Anthrax Toxemia by Hexa-D-Arginine In Vitro and In Vivo[J]. Infection and Immunity, 2004, 72(1):602-605.

Other Notes

Small volumes of Hexa-D-arginine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hexa-D-arginine purchase

MBS5758389 is an inhibitor targeting Hexa-D-arginine.
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