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zanubrutinib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758476

MBS5758476 is an inhibitor targeting zanubrutinib. Zanubrutinib is an inhibitor of Bruton tyrosine kinase (BTK). More details

Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
zanubrutinib, Inhibitor
Full Product Name
zanubrutinib
Product Synonym Names
BGB-3111
Form/Format
Solid. Powder
Purity/Purification
99.74%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
471.55
Solubility
DMSO: 56.75mg/mL (120.35mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C27H29N5O3
SMILES
C=CC(=O)N1CCC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1
CAS Number
1691249-45-2
Target & IC50
BTK

Product Categories/Family for zanubrutinib, inhibitor

Product References and Citations for zanubrutinib, inhibitor

Li N, Sun Z, Liu Y, et al. Abstract 2597: BGB-3111 is a novel and highly selective Bruton's tyrosine kinase (BTK) inhibitor[J]. Cancer Research, 2015, 75(15 Supplement):2597-2597.
Li N, Sun Z, Liu Y, et al. Abstract 2597: BGB-3111 is a novel and highly selective Bruton's tyrosine kinase (BTK) inhibitor[J]. Cancer Research, 2015, 75(15 Supplement):2597-2597.
Chiara Tarantelli, Lu Zhang, Elisabetta Curti,et al. The Bruton Tyrosine Kinase Inhibitor Zanubrutinib (BGB-3111) Demonstrated Synergies With Other Anti-Lymphoma Targeted Agents[J].Haematologica, 104 (7), e307-e309 Jul 2019
Chiara Tarantelli, Lu Zhang, Elisabetta Curti,et al. The Bruton Tyrosine Kinase Inhibitor Zanubrutinib (BGB-3111) Demonstrated Synergies With Other Anti-Lymphoma Targeted Agents[J].Haematologica, 104 (7), e307-e309 Jul 2019
Na Li, et al. Abstract 2597: BGB-3111 is a novel and highly selective Bruton's tyrosine kinase (BTK) inhibitor. Cancer Res 2015;75(15 Suppl):Abstract nr 2597.

Other Notes

Small volumes of zanubrutinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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