L-DAB HBR Inhibitor

Name: L-DAB HBR Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758483
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758483

MBS5758483 is an inhibitor targeting L-DAB HBR. L-DAB HBR is an inhibitor of GABA transaminase (IC50 > 500uM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

L-DAB HBR, Inhibitor

Full Product Name

L-DAB HBR

Product Synonym Names

L-2,4-Diaminobutyric acid

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

118.13

Solubility

H2O: 34mg/mL (287.82mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C4H10N2O2

SMILES

NCC[C@H](N)C(=O)O

CAS Number

1758-80-1

Target & IC50

GABA
Human Endogenous Metabolite

In Vitro

L-2,4-Diaminobutyric acid(DABA) was a non-linear, non-competitive inhibitor of GABA transaminase activity. The DABA-induced elevation of GABA levels paralleled the inhibition of GABA transaminase activity. DABA was a more effective inhibitor of GABA transaminase in vivo than in vitro, and this inhibition probably produced the elevation of GABA levels. The neurotoxicity of DABA appears to produce a use in GABA replacement therapy[1].

Product Categories/Family for L-DAB HBR, inhibitor

Neuroscience; Membrane transporter/Ion channel; Metabolic Enzyme/Protease

Product References and Citations for L-DAB HBR, inhibitor

Beart P M, Bilal K. l-2,4-Diaminobutyric acid and the GABA system[J]. Neuroscience Letters, 1977, 5(3-4):193-198.
Beart P M, Bilal K. l-2,4-Diaminobutyric acid and the GABA system[J]. Neuroscience Letters, 1977, 5(3-4):193-198.
Ronquist G, Hugosson R, Westermark B. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo.[J]. Journal of Cancer Research & Clinical Oncology, 1980, 96(3):259-68.
Ronquist G, Hugosson R, Westermark B. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo.[J]. Journal of Cancer Research & Clinical Oncology, 1980, 96(3):259-68.

Other Notes

Small volumes of L-DAB HBR, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

L-DAB HBR Inhibitor

Product Overview

Product Categories/Family for L-DAB HBR, inhibitor

Structure of L-DAB HBR, inhibitor

Related Product Information for L-DAB HBR, inhibitor

Product References and Citations for L-DAB HBR, inhibitor

Other Notes