• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Avermectin B1a Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758493

MBS5758493 is an inhibitor targeting Avermectin B1a. Avermectin B1a is a macrocyclic lactone disaccharide anthelmintic agent. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Avermectin B1a, Inhibitor
Full Product Name
Avermectin B1a
Product Synonym Names
Abamectin B1a; Avamectin B1a
Form/Format
Solid. Powder
Purity/Purification
95.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
873.08
Solubility
DMSO: 100mg/mL (114.54mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C48H72O14
SMILES
CCC(C)C1OC2(C=CC1C)CC1CC(C/C=C(\C)C(OC3CC(OC)C(OC4CC(OC)C(O)C(C)O4)C(C)O3)C(C)/C=C/C=C3\COC4C(O)C(C)=CC(C(=O)O1)C34O)O2
CAS Number
65195-55-3
Target & IC50
Parasite
In Vitro
The binding of the glycine receptor antagonist, strychnine, to both membranes and solubilized receptor from rat spinal cord, was inhibited by avermectin B1a with Ki values of 1.3microM and 3.6microM, and Hill coefficients of 0.46 and 0.62, respectively[1].

Product Categories/Family for Avermectin B1a, inhibitor

Microbiology&virology

Structure of Avermectin B1a, inhibitor

Avermectin B1a Inhibitor – Cat# MBS5758493

Product References and Citations for Avermectin B1a, inhibitor

Graham D, Pfeiffer F, Betz H. Avermectin B1a inhibits the binding of strychnine to the glycine receptor of rat spinal cord[J]. Neuroscience Letters, 1982, 29(2):173-176.
Graham D, Pfeiffer F, Betz H. Avermectin B1a inhibits the binding of strychnine to the glycine receptor of rat spinal cord[J]. Neuroscience Letters, 1982, 29(2):173-176.
Payne G T, Soderlund D M. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a[J]. 1991, 6(4):283-292.
Payne G T, Soderlund D M. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a[J]. 1991, 6(4):283-292.

Other Notes

Small volumes of Avermectin B1a, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000