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Neurotensin (3TFA) Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758506

Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neurotensin (3TFA), Inhibitor
Full Product Name
Neurotensin (8-13) (3TFA)
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
816.99
Solubility
H2O: 50mg/mL (61.20mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C38H64N12O8
SMILES
CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCCN1C(=O)C(CCCNC(=N)N)NC(=O)C(N)CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)O
CAS Number
60482-95-3
Target & IC50
NTR1
In Vitro
The internalization of the receptor induced by neurotensin (8-13) leads to a decrease in the density of the NT1 receptor (NTR1) on the cell surface. In ht-29 cells and rat primary cultured neurons, the neurotensin (NT) receptor was down-regulated by high concentrations of extracellular peptides. The representation of cell surface receptors is also different[1]

Structure of Neurotensin (3TFA), inhibitor

Neurotensin (3TFA) Inhibitor – Cat# MBS5758506

Product References and Citations for Neurotensin (3TFA), inhibitor

Elisa Garcia-Garayoa, Peter Blauenstein, Bruehlmeier M, et al. Preclinical evaluation of a new, stabilized neurotensin(8-13) pseudopeptide radiolabeled with 99mTc[J]. Journal of Nuclear Medicine, 2002, 43(3):374-383.
Elisa Garcia-Garayoa, Peter Blauenstein, Bruehlmeier M, et al. Preclinical evaluation of a new, stabilized neurotensin(8-13) pseudopeptide radiolabeled with 99mTc[J]. Journal of Nuclear Medicine, 2002, 43(3):374-383.
Cusack, B. Proposed Ligand Binding Site of the Transmembrane Receptor for Neurotensin(8-13)[J]. Journal of Biological Chemistry, 1996, 271(25):15060-15068.
Cusack, B. Proposed Ligand Binding Site of the Transmembrane Receptor for Neurotensin(8-13)[J]. Journal of Biological Chemistry, 1996, 271(25):15060-15068.

Other Notes

Small volumes of Neurotensin (3TFA), inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Neurotensin (3TFA) purchase

MBS5758506 is an inhibitor targeting Neurotensin (3TFA). Also known as Neurotensin (8-13) (3TFA).
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