Bisindolylmaleimide IV Inhibitor

Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55uM)

Toullec D, Pianetti P, Coste H, et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.[J]. Journal of Biological Chemistry, 1991, 24(24):15771-1578
Toullec D, Pianetti P, Coste H, et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.[J]. Journal of Biological Chemistry, 1991, 24(24):15771-15781.
Davis P D, Hill C H, Lawton G, et al. Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides[J]. Journal of Medicinal Chemistry, 1992, 35(1):177-184.
Davis P D, Hill C H, Lawton G, et al. Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides[J]. Journal of Medicinal Chemistry, 1992, 35(1):177-184.

Small volumes of Bisindolylmaleimide IV, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5758551 is an inhibitor targeting Bisindolylmaleimide IV.